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There are several things that contribute to hangovers, but one of the
principal factors is simple dehydration. Alcohol has a dehydrating
effect by inhibiting the release of vasopressin, which is an
anti-diuretic hormone. So, in layman’s terms, the result of alcohol
inhibiting the vasopressin is that your body produces a lot more urine
than normal, with the result that you become dehydrated easily.
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